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Expression of the platelet‐common acute lymphoblastic leukaemia associated antigen on normal eosinophils
Author(s) -
Ohto H.,
Shibata Y.,
Takeuchi A.,
Chen RF.,
Maeda H.
Publication year - 1985
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1985.tb02793.x
Subject(s) - platelet , immunology , antigen , monoclonal antibody , eosinophil , antibody , medicine , asthma
A murine monoclonal antibody (TP82) raised against normal platelets was found to be reactive with eosinophils and common acute lymphoblastic leukaemia (cALL) cells, and some blast cells from patients with non‐lymphoid leukaemia. The antibody showed that the platelet‐cALL associated antigen (p24) is also expressed on normal eosinophils, and may prove useful for studying the function as well as the differentiation of eosinophils.