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Lysosomal Enzyme Activities in a Case of T‐Cell Chronic Lymphocytic Leukaemia
Author(s) -
Crockard A. D.,
Morris T. C. M.
Publication year - 1981
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1981.tb01393.x
Subject(s) - enzyme , chronic lymphocytic leukemia , glucuronidase , biology , immunology , microbiology and biotechnology , chemistry , leukemia , biochemistry
This study indicated that (i) high levels of N‐acetyl‐β‐glucosaminidase and β‐glucuronidase could be demonstrated cytochemically in T‐CLL lymphocytes, and (ii), the biochemical activities of both enzymes were significantly increased in T‐CLL lymphocytes compared with B‐CLL lymphocytes. It would appear that the biochemical and cytochemical determination of these lysosomal enzyme activities offers an additional means of distinguishing T‐CLL and B‐CLL lymphocytes.