Non‐Randomness in Complex Translocations of Chronic Myeloid Leukaemia | Zendy

Berger Roland | Zendy; Bernheim Alain | Zendy

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Non‐Randomness in Complex Translocations of Chronic Myeloid Leukaemia

Author(s) -

Berger Roland,

Bernheim Alain

Publication year - 1978

Publication title -

scandinavian journal of haematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.904

H-Index - 84

eISSN - 1600-0609

pISSN - 0036-553X

DOI - 10.1111/j.1600-0609.1978.tb00388.x

Subject(s) - chromosomal translocation , chronic myeloid leukaemia , randomness , chromosome , karyotype , biology , genetics , disease , medicine , immunology , pathology , gene , mathematics , statistics

A new case of chronic myeloid leukaemia with a complex translocation involving chromosomes No. 1, 9 and 22 is reported. The striking similarity of this case with another previously reported case and the involvement of band 9q34 in chromosome rearrangements in CML patients indicates clearly a non‐randomness of chromosome abnormalities in this blood disease, even when the translocation is different from the usual t(9;22) one. The usefulness of R‐banding techniques is emphasized in these cases.

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