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Membrane Activity in Juvenile Xanthogranuloma
Author(s) -
Seifert Heinz W.
Publication year - 1981
Publication title -
journal of cutaneous pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 75
eISSN - 1600-0560
pISSN - 0303-6987
DOI - 10.1111/j.1600-0560.1981.tb00982.x
Subject(s) - juvenile xanthogranuloma , pathology , juvenile , medicine , dermatology , biology , histiocyte , genetics
In a case of juvenile xanthogranuloma in an early stage, electron microscopic examination revealed membrane activity resulting in complex interdigitations with subsequent transformation into aggregated cytoplasmic vesicles. Similar membrane complexes were encountered in multinucleated giant cells and they may be a result of endocytosis or remnants of cell membranes of fused macrophages. Other findings were “virus‐like inclusions” in histiocytes and giant cells, intracytoplasmic collagen in fibroblasts and “cross‐banded filamentous aggregations”.