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Contact urticaria from diethyl fumarate
Author(s) -
Lahti Arto,
Maibach Howard I.
Publication year - 1985
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1985.tb01082.x
Subject(s) - guinea pig , contact urticaria , dimethyl fumarate , contact dermatitis , human skin , patch testing , allergic contact dermatitis , skin reaction , chemistry , dermatology , medicine , immunology , allergy , biology , multiple sclerosis , genetics
The contact urticariagenic properties of diethyl fumarate were studied using the guinea pig ear swelling assay and by open application on the human upper back skin. Diethyl fumarate caused non‐immunologic contact urticaria in both human and guinea pigskin, and the reactions exhibited similar dose dependency and timing of maximal response.