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The comparative effects on plaque regrowth of phenolic chlorhexidine and anti‐adhesive mouthrinses
Author(s) -
Moran J.,
Addy M.,
Newcombe R.,
Warren P.
Publication year - 1995
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/j.1600-051x.1995.tb01797.x
Subject(s) - chlorhexidine , washout , dental plaque , crossover study , dentistry , medicine , in vivo , placebo , alternative medicine , microbiology and biotechnology , pathology , biology
Abstract The inhibition of bacterial attachment to the tooth surface is one possible approach to plaque control. This study evaluated in vivo the plaque inhibitory action of a novel copolymer reported to have considerable antiadhesive properties in vitro. The study was a single blind. 5‐treatment. randomised Latin square crossover design, incorporating balance for carry‐over effects. The rinses were the antiadhesive (1%), the antiadhesive with 0.02% chlorhexidine, a 0.2% chlorhexidine rinse product, an essential oil/phenolic rinse product and water. 15 volunteers participated and on day 1 of each study period were rendered plaque‐free, ceased toothcleaning and rinsed 2x daily. under supervision, with the allocated formulation. On day 5, plaque was scored by index and area. Washout periods were 21/2 days. Alone or combined with chlorhexidine, the antiadhesive agent showed no effects greater than water. The chlorhexidine rinse was significantly more effective than the essential oil/phenolic rinse which in turn was significantly more effective than the other rinses.