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Epileptogenesis: Contributions of calcium ions and antiepileptic calcium antagonists
Author(s) -
Walden J.,
Straub H.,
Speckmann E. J.
Publication year - 1992
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1992.tb04469.x
Subject(s) - epileptogenesis , calcium , epilepsy , neuroscience , pharmacology , medicine , psychology
The results demonstrate that organic calcium antagonists are able to reduce epileptic activity at the level of single neurons and of neuronal populations. This holds true also for human cortical tissue. Among other observations already published this justifies the hope that calcium antagonistic agents might be useful in the treatment of human epilepsies (28).