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Expression of complement C3b/C4b receptors (CR1) on erythrocytes from patients with myasthenia gravis
Author(s) -
Vedeler C. A.,
Gilhus N. E.,
Matre R.
Publication year - 1990
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1990.tb01616.x
Subject(s) - myasthenia gravis , receptor , hemagglutination , immunology , complement system , complement (music) , medicine , acetylcholine receptor , complement receptor , antibody , biology , gene , biochemistry , complementation , phenotype
The complement C3b/C4b receptor (CR1) expression on erythrocytes (E) (ECR1) from patients with myasthenia gravis (MG) and from blood donors was measured using haemadsorption and indirect heamagglutination techniques. The ECR1 expression in patients with MG appeared to be normal. This was also true for the subgroup of MG patients with additional autoimmune diseases. No correlation between ECR1 expression and severity of myasthenic symptoms was demonstrated.
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