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Multiple sclerosis and macrocytosis
Author(s) -
Crellin R. F.,
Bottiglieri T.,
Reynolds E. H.
Publication year - 1990
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1990.tb00981.x
Subject(s) - macrocytosis , multiple sclerosis , vitamin b12 , medicine , vitamin b , gastroenterology , immunology , vitamin
Twenty‐seven patients with multiple sclerosis had mild but significant macrocytosis when compared with an individually matched neurological control group and the normal laboratory reference range. The cause of the macrocytosis is unknown, but our recent clinical observations implicate a possible disturbance in vitamin B12 metabolism, binding or transport.