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Antioxidant treatment in Spielmeyer‐Sjögren's disease
Author(s) -
Santavuori Pirkko,
Westermarck Tuomas,
Rapola Juhani,
Pohja Paula,
Moren Riitta,
Lappi Marjatta,
Vuonnala Ulla
Publication year - 1985
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1985.tb03178.x
Subject(s) - antioxidant , vitamin e , medicine , selenium , disease , vitamin c , gastroenterology , pediatrics , chemistry , biochemistry , organic chemistry
– The data for 125 patients with Spielmeyer‐Sjögren's disease is presented. Antioxidant therapy was given to 49. 27 received a combination of vitamin E, vitamin C, methionine and BHT. As the disease began to progress, the treatment was changed to a combintion of sodium selenite and vitamin E in 14 of the 27 patients. The same therapy was also given to 22 children who had not received previous antioxidant supplementation. The number of positive and negative responses was nearly equal in the 2 treatment groups. However, the quality of the response was better in the selenite group and it has been possible in some cases to stop for several years, at least, the deterioration which began during the original therapy.