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EEG monitoring of focal lesions of the blood‐brain barrier
Author(s) -
Remler Michael P.,
Marcussen William H.
Publication year - 1982
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1982.tb03061.x
Subject(s) - electroencephalography , penicillin , focus (optics) , encephalopathy , blood–brain barrier , epilepsy , medicine , neuroscience , pathology , central nervous system , psychology , antibiotics , chemistry , physics , optics , biochemistry
This paper presents a modified method for the EEG detection and monitoring of small focal blood‐brain barrier (BBB) lesions. The method uses high dose IV penicillin (1.2 x 10 6 μ/kg) to produce a spike focus at BBB lesions, penicillin encephalopathy. The EEG is recorded and the epileptic spikes are counted by an automatic computer program. The computer counting produces an objective quantitative result. The method is verified empirically on traumatic and radiation BBB lesions.