Open AccessThe effect of Cyclosporine A on cardiomyocytes differentiation
Author(s) -
Paslaru Liliana,
Davidson Sean,
Popescu Irinel,
Morange Michel
Publication year - 2007
Publication title -
journal of cellular and molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.44
H-Index - 130
eISSN - 1582-4934
pISSN - 1582-1838
DOI - 10.1111/j.1582-4934.2007.00029.x
Subject(s) - limiting , drug , pharmacology , immunosuppressive drug , adverse effect , medicine , organ transplantation , transplantation , mechanical engineering , engineering
Cyclosporine A (CsA) is a powerful immunosuppressive drug which significantly improved the success of organ transplantation; however, the major limiting factors for the drug's clinical use are its long and short term adverse effects. The present study was conducted to examine, in a dose‐dependent manner, in a model of cardiogenesis, the effect of CsA on cardiomyocytes differentiation.