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Atrial Selective Effect of Amiodarone to Increase Threshold of Excitation
Author(s) -
GRANDE JUAN MANUEL,
GRANDE ANGEL,
MOLINA MARIA,
NOVO CAROLINA,
CABESTRERO FERNANDO
Publication year - 2013
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2011.03272.x
Subject(s) - amiodarone , medicine , cardiology , anesthesia , atrial fibrillation
Increases of pacing threshold stimulation are well documented with different antiarrhythmic drugs, but not with amiodarone. We report a case of a patient with dual‐chamber pacing, with stable thresholds on repeated measurements on the last year, who presented severe increase of atrial pacing threshold resulting in loss of atrial capture after a year of treatment with amiodarone. Thresholds were normalized once amiodarone was removed. Ventricular thresholds were not affected.

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