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His‐Purkinje System Reentry As a Pro arrhythmic Effect of Flecainide
Author(s) -
CHALVIDAN T.,
CELLARIER G.,
DEHARO J.C.,
COLIN R.,
SAVON N.,
BARRA N.,
PEYRE J.P.,
DJIANE P.
Publication year - 2000
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2000.tb00841.x
Subject(s) - flecainide , medicine , reentry , cardiology , ajmaline , ventricular tachycardia , left bundle branch block , right bundle branch block , tachycardia , anesthesia , electrocardiography , atrial fibrillation , heart failure
We report a case of tachycardia due to reentry within the His‐Purkinje system (HPS) occurring after introduction of flecainide. The patient presented with a mild mitral regurgitation and normal left ventricular function. He had incomplete left bundle branch block with left‐axis deviation. At the electrophysiology study, a prolonged HV interval was observed at baseline, and the tachycardia could be reproduced after ajmaline infusion. Six months after interruption of flecainide, the patient remains free of arrhythmia recurrence. The authors emphasize that proarrhythmic effects of flecainide may include reentry within the HPS in patients with underlying HPS disease.