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A Protease TAMER: a nucleic acid‐based anticoagulant
Author(s) -
FREDENBURGH J. C.,
KRETZ C. A.,
WEITZ J. I.
Publication year - 2012
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/j.1538-7836.2012.04684.x
Subject(s) - aptamer , systematic evolution of ligands by exponential enrichment , thrombin , chemistry , pharmacology , druggability , oligonucleotide , microbiology and biotechnology , computational biology , biochemistry , medicine , biology , rna , dna , immunology , platelet , gene
See also Bompiani KM, Monroe DM, Church FC, Sullenger BA. A high affinity, antidote‐controllable prothrombin and thrombin‐binding RNA aptamer inhibits thrombin generation and thrombin activity. This issue, pp 870–80.