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The Combined Effect of Alcohol and Physical Exercise on Serum Testosterone, Luteinizing Hormone, and Cortisol in Males
Author(s) -
Heikkonen Erkki,
Ylikahri Reino,
Roine Risto,
Välimäki Matti,
Härkönen Matti,
Salaspuro Mikko
Publication year - 1996
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1996.tb01676.x
Subject(s) - testosterone (patch) , luteinizing hormone , alcohol , endocrinology , medicine , hormone , body weight , alcohol intoxication , physical exercise , poison control , chemistry , injury prevention , biochemistry , environmental health
The combined effect of alcohol and physical exercise on the serum levels of testosterone, luteinizing hormone, and cortisol was studied in healthy male volunteers by performing an exhaustive ergometer exercise (1) followed by alcohol intoxication (induced by 1.5 g of alcohol/kg body weight), (2) during alcohol intoxication (induced by 0.8 g of alcohol/kg body weight), and (3) during hangover (13 hr after a dose of 1.5 g of alcohol/kg body weight). Physical stress immediately before alcohol administration prolonged the depressant effect of alcohol on testosterone secretion. This seemed to be mainly a consequence of direct inhibition at the testicular level, even though the role of luteinizing hormone as a contributory regulatory factor cannot be totally ruled out. Cortisol response to exercise was not modified by alcohol under any of the experimental conditions.