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Endocrine Effects of Maternal Alcoholization: Plasma and Brain Testosterone, Dihydrotestosterone, Estradiol, and Corticosterone
Author(s) -
Kakihana Ryoko,
Butte John C.,
Moore Jerome A.
Publication year - 1980
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1980.tb04792.x
Subject(s) - endocrinology , medicine , dihydrotestosterone , testosterone (patch) , corticosterone , offspring , hormone , endocrine system , ethanol , androgen , chemistry , biology , pregnancy , genetics , organic chemistry
Maternal ethanol consumption was associated with reduced levels of dihydrotestosterone in the brains of 1–2‐day‐old male rats when compared to those of sex‐matched pups obtained from dames that were fed sucrose. In contrast, brain levels of corticosterone were increased significantly in the pups of ethanol‐fed animals when compared to those from sucrose‐fed controls. Brain and plasma estradiol did not differ between groups. These results suggest that maternal ethanol consumption may influence the central nervous system and plasma levels6000 of certain steroidal hormones in the offspring.