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Efficacy of a new fractional CO 2 laser in the treatment of photodamage and acne scarring
Author(s) -
Katz Bruce
Publication year - 2010
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/j.1529-8019.2010.01340.x
Subject(s) - medicine , acne , dermatology , acne scars
This study evaluates the efficacy and safety of a novel fractional CO 2 laser device for improving facial rhytids, hyperpigmentation, enlarged pores, skin laxity, and acne scarring. Subjects ( n = 15) were treated three to five times at 3‐week intervals. Biopsy specimens were used to evaluate healing response and neocollagenesis. Clinical improvement was rated on a quartile rating scale from digital photographs. Subject discomfort during treatment was evaluated on a scale of 0 to 5. Fourteen subjects who completed the study achieved good to excellent improvement in overall appearance, with 60% rated excellent. Improvement in photodamage was good to excellent in 92% of subjects, and reduction in rhytids was good to excellent in 85%. A total of 79% of subjects achieved good to excellent improvement in pore sizes and skin laxity. Subject discomfort during treatment was 3.0 ± 0.7. Erythema persisted for 2–3 days, and subjects resumed normal activities 1–2 days after the procedure. Histological slides after a single treatment showed new collagen formation. The SmartSkin fractional CO 2 system (Cynosure, Inc., Westford, MA, USA) provides significant improvement for the treatment of facial wrinkles, hyperpigmentation, pore size, and skin laxity associated with photodamage.