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Risk Factors for Developing Seizures After a Stroke
Author(s) -
Lancman Marcelo Elias,
Golimstok Angel,
Norscini Jorge,
Granillo Rubens
Publication year - 1993
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1157.1993.tb02386.x
Subject(s) - stroke (engine) , epilepsy , medicine , clinical neurology , psychology , neuroscience , psychiatry , mechanical engineering , engineering
Summary: We evaluated development of seizures in 219 consecutive patients who had ischemic or hemorrhagic stroke. Subjects with transitory ischemic attacks, sub‐arachnoid, subdural, and epidural hemorrhages or those with previous history of epilepsy were excluded. Mean follow‐up time was 11.5 months (range 1–72 months). Twenty‐two of 219 stroke patients (10.04%) had seizures. Twelve (54.55%) were of early onset (<1 month after the stroke), and 10 (45.45%) were of late onset. No statistically significant differences were evident between the early‐ and late‐onset seizure group in comparisons of type of stroke, localization, and size of the lesion. Six of 22 patients (27%) had seizure recurrence. Seizures developed in (a) 13 of 183 patients with ischemic stroke (7.1%) and 9 of 36 patients with hemorrhagic stroke (25%) (p = 0.01); (b) 16 of 93 patients with cortical lesions (17%) and 6 of 126 patients with subcortical lesions (4.7%) (p = 0.01); and (c) 14 of 66 patients with a lesion comprising more than one lobe (21.2%) and 8 of 153 patients with a lesion comprising less than one lobe (5.2%) (p < 0.01). We conclude that patients with hemorrhagic stroke, cortical lesions, and lesions involving more than one lobe are at higher risk of developing seizures.