Open AccessVasopeptidase Inhibition and its Role in Congestive Heart Failure
Author(s) -
Sica Domenic A.
Publication year - 2000
Publication title -
congestive heart failure
Language(s) - English
Resource type - Journals
eISSN - 1751-7133
pISSN - 1527-5299
DOI - 10.1111/j.1527-5299.2000.80153.x
Subject(s) - medicine , heart failure , neprilysin , pharmacology , cardiology , enzyme , biochemistry , chemistry
Vasopeptidase inhibition—that is, the dual inhibition of ACE and neutral endopeptidase—reduces blood pressure in a potent manner. Preliminary studies suggest that vasopeptidase inhibition can also effectively treat congestive heart failure. Additional corroborating studies to support the use of vasopeptidase inhibition in heart failure are now underway.