Premium
Pentoxifylline and Cyclosporine in the Treatment of Febrile Ulceronecrotic Mucha‐Habermann Disease
Author(s) -
Uzoma Miranda A.,
Wilkerson Michael G.,
Carr Vicki L.,
Westhoven Gail S.,
Raimer Sharon A. S.
Publication year - 2012
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.2012.01862.x
Subject(s) - pentoxifylline , medicine , disease , pharmacology , immunology
We describe two pediatric cases of febrile ulceronecrotic Mucha‐Habermann disease (FUMHD) with response to pentoxifylline and cyclosporine therapies. Based on our review of the literature, we are presenting the first case of FUMHD treated with pentoxifylline and the third case of FUMHD successfully treated with cyclosporine. These agents may be of therapeutic benefit in the treatment of FUMHD, in part by suppressing tumor necrosis factor‐alpha, which we believe may mediate the disease process.