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Dramatic Response of Choroidal Metastases from Breast Cancer to a Combination of Trastuzumab and Vinorelbine
Author(s) -
Wong ZeeWan,
Phillips Steven J.,
Ellis Matthew J.
Publication year - 2004
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/j.1524-4741.2004.09614.x
Subject(s) - vinorelbine , medicine , trastuzumab , breast cancer , oncology , radiation therapy , chemotherapy , cancer , radiology , cisplatin
  We report the case of a 57‐year‐old woman with unilateral choroidal metastases from HER‐2‐positive breast cancer. She was given trastuzumab and vinorelbine with complete resolution of her visual defect after one cycle of treatment. This article illustrates that treatment using trastuzumab‐containing chemotherapy regimens in HER‐2‐overexpressing breast cancer patients with choroidal metastases may be an alternative therapeutic strategy to initial orbital irradiation. 

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