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Associations Between ADHD and Psychoactive Substance Use Disorders
Author(s) -
Milberger Sharon,
Biederman Joseph,
Faraone Stephen V.,
Wilens Timothy,
Chu Monica P.
Publication year - 1997
Publication title -
the american journal on addictions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.997
H-Index - 76
eISSN - 1521-0391
pISSN - 1055-0496
DOI - 10.1111/j.1521-0391.1997.tb00413.x
Subject(s) - psychiatry , comorbidity , proband , attention deficit hyperactivity disorder , psychoactive substance , psychology , conduct disorder , substance use , clinical psychology , addiction , medicine , biochemistry , chemistry , mutation , gene
This article investigates the relationship between attention‐deficit/hyperactivity disorder (ADHD) and psychoactive substance use disorders (PSUD) in siblings of ADHD and normal‐control probands and addresses issues of psychiatric comorbidity and gender. Using DSM‐III‐R structured diagnostic interviews and blind raters, the authors conducted a 4‐year follow‐up of siblings. ADHD and male gender predicted higher rates and an earlier onset of PSUD after adjusting for high‐risk status, other psychiatric disorders, and age. Risk was particularly high if the siblings had ADHD plus conduct disorder. This study's findings confirms the authors' prior report highlighting the importance of drug and alcohol prevention and cessation programs aimed at ADHD youth and their siblings, particularly those with comorbid conduct disorder.

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