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ANTICOAGULANT EFFECTS OF SULPHATED POLYSACCHARIDES IN NORMAL AND ANTITHROMBIN III‐DEFICIENT PLASMAS
Author(s) -
KINDNESS G.,
LONG W.F.,
WILLIAMSON F.B.
Publication year - 1980
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1980.tb07921.x
Subject(s) - antithrombin , polysaccharide , thrombin , chemistry , anticoagulant , heparin , coagulation , biochemistry , antithrombins , pharmacology , medicine , platelet
1 Comparison of the effects of sulphated polysaccharides on thrombin‐induced clotting of normal and antithrombin III‐deficient plasmas suggests the involvement of antithrombin III (AT III) in the anticoagulant activities of cellulose, dextran and xylan sulphates. 2 AT III appears to play little or no role in the anticoagulant activity of carrageenans.