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Free and Conjugated Amines in Human Lumbar Cerebrospinal Fluid
Author(s) -
Tyce Gertrude M.,
Rorie Duane K.,
Byer David E.,
Danielson David R.
Publication year - 1985
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1985.tb07149.x
Subject(s) - cerebrospinal fluid , conjugated system , lumbar , chemistry , medicine , pathology , anatomy , organic chemistry , polymer
Significant amounts of acid‐hydrolyzable conjugates of 3,4‐dihydroxyphenylethylamine, norepinephrine, and 5‐hydroxytryptamine were detected in lumbar CSF from 22 awake unpremedicated healthy individuals. In the CSF samples, the amounts of conjugated amines almost always exceeded the amounts of free amines, but were less than the amounts of the acid metabolites 3,4‐dihydroxyphenylacetic acid, homovanillic acid, and 5‐hydroxyindoleacetic acid.