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Elevated Amounts of Protein in C6 Glial Cells During the Growth‐Inhibitory Response Elicited by Dexamethasone
Author(s) -
Grasso Robert J.,
Holbrook Nikki J.,
Wodzinski Steven F.
Publication year - 1981
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1981.tb00486.x
Subject(s) - inhibitory postsynaptic potential , dexamethasone , chemistry , neuroglia , neuroscience , endocrinology , microbiology and biotechnology , biology , central nervous system
Dexamethasone suppresses C6 glial cell proliferation in vitro. This growth‐inhibitory response is accompanied by elevated amounts of acid‐insoluble protein in the steroid‐treated cells relative to controls. These results provide additional evidence that the glucocorticoid acts to arrest C6 cell proliferation in G2.