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Phosphatidylinositol Labelling in Response to Activation of Muscarinic Receptors in Bovine Adrenal Medulla
Author(s) -
Mohd. Adnan N. A.,
Hawthorne J. N.
Publication year - 1981
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/j.1471-4159.1981.tb00441.x
Subject(s) - muscarinic acetylcholine receptor , adrenal medulla , phosphatidic acid , labelling , phosphatidylinositol , endocrinology , chemistry , nicotinic agonist , medulla , catecholamine , medicine , secretion , muscarinic acetylcholine receptor m3 , receptor , biology , biochemistry , signal transduction , phospholipid , membrane
The secretion of catecholamines and the labelling of phospholipids with 32 P i has been studied in slices of bovine adrenal medulla. Both nicotinic and muscarinic drugs provoked catecholamine secretion, but only muscarinic activation was accompanied by the increased labelling of phosphatidylinositol and phosphatidic acid.