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Radical trachelectomy in early stage carcinoma of the cervix: outcome as judged by recurrence and fertility rates
Author(s) -
Shepherd John H.,
Mould Tim,
Oram David H.
Publication year - 2001
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2001.00212.x
Subject(s) - trachelectomy , medicine , fertility , radical hysterectomy , cervix , miscarriage , cervical cancer , obstetrics , stage (stratigraphy) , gynecology , cervical cerclage , pregnancy , cancer , gestational age , population , paleontology , environmental health , biology , genetics
The recurrence and fertility rates in 30 women undergoing radical trachelectomy for early stage invasive cervical cancer at St Bartholomew's and Royal Marsden Hospital were reviewed. There were no recurrences, and the mean follow up was 23 months (range 1–64 months). Of 13 women trying to have a baby, eight had conceived with a total of 14 pregnancies and nine live births. Two were still trying and three were experiencing sub‐fertility. There were seven premature deliveries and one late miscarriage. Six of the preterm births and the late miscarriage were associated with prelabour spontaneous rupture of membranes. This conservative yet locally radical procedure for a highly selected group of women who wished to preserve their fertility appears to offer a safe alternative to radical hysterectomy in early invasive cervical cancer.