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B cell leukaemia/lymphoma‐2 protein concentrations during normal pregnancy
Author(s) -
Buemi M.,
Allegra A.,
Corica F.,
D'Anna R.,
Ruello A.,
Jasonni V. M.
Publication year - 2000
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.2000.tb11591.x
Subject(s) - pregnancy , lymphoma , endocrinology , medicine , andrology , chemistry , immunology , biology , physiology , genetics
We evaluated bcl‐2 protein levels in whole blood, and intraerythrocytic products of lipoperoxidation, in 65 healthy pregnant primiparous women at the end of the first, second and third trimesters of pregnancy. During pregnancy we found a progressive increase in concentrations of bcl‐2 and intraerythrocytic products of lipoperoxidation. Moreover, a positive correlation was found between bcl‐2 concentrations and lipoperoxidation products, and between bcl‐2 protein, E 2 and progesterone. The results show that modifications occurring during pregnancy are accompanied by variations of bcl‐2 protein.