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A SIMPLE AND SENSITIVE RADIOIMMUNOASSAY FOR PREGNANCY‐SPECIFIC β 1 ‐GLYCOPROTEIN
Author(s) -
Towler C. M.,
Horne C. H. W.,
Jandial V.,
Chesworth J. M.
Publication year - 1977
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1977.tb12657.x
Subject(s) - radioimmunoassay , simple (philosophy) , glycoprotein , pregnancy , computer science , chromatography , obstetrics , chemistry , medicine , biology , biochemistry , philosophy , genetics , epistemology
Summary A simple, sensitive and relatively rapid radioimmunoassay for pregnancy‐specific β 1 ‐glycoprotein (PSβG) is described. The concentrations of PSβG in plasma from cord blood and in amniotic fluid were approximately 0·1 per cent and 1·0 per cent respectively of the maternal plasma levels. The amniotic fluid PS(3G levels in pregnancies associated with an anencephalic fetus were not significantly different from normal levels.