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THE RESPONSE OF LYMPHOCYTES TO PHYTOHAEMAGGLUTININ IN WOMEN WITH PRE‐ECLAMPSIA
Author(s) -
Need Jillian A.,
Jenkins D. M.,
Scott J. S.
Publication year - 1976
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/j.1471-0528.1976.tb00861.x
Subject(s) - phytohaemagglutinin , eclampsia , pregnancy , immunosuppression , medicine , abnormality , immunology , endocrinology , lymphocyte , biology , genetics , psychiatry
Summary The response of maternal lymphocytes to phytohaemagglutinin was determined during and after pregnancy in patients with severe pre‐eclampsia and in controls. The patients with pre‐eclampsia showed a greater degree of immunosuppression during pregnancy than the normotensive controls. This was apparent in the presence and absence of maternal serum. In pre‐eclampsia there may be an abnormality affecting the T cell subpopulation of lymphocytes and also a decreased immunosuppressive effect of maternal serum.