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Polymorphism of human C5
Author(s) -
HOBART M. J.,
GUEDES M. A. VAZ,
LACHMANN P. J.
Publication year - 1981
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1981.tb00299.x
Subject(s) - genetics , isoelectric focusing , biology , inheritance (genetic algorithm) , human leukocyte antigen , polymorphism (computer science) , linkage (software) , allele , gene , antigen , biochemistry , enzyme
SUMMARY C5 is polymorphic in Melanesians and related peoples. The polymorphism is demonstrated by isoelectric focusing and functional detection. Inheritance is autosomal and codominant. Preliminary linkage data suggest that C5 is not close to HLA.