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Livedo reticularis associated with interferon α therapy in two melanoma patients
Author(s) -
RuizGenao DP,
GarcíaFVillalta MJ,
HernándezNúñez A,
RíosBuceta L,
FernándezHerrera J,
GarcíaDíez A
Publication year - 2005
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2004.01128.x
Subject(s) - medicine , livedo reticularis , alpha interferon , melanoma , interferon , dermatology , adjuvant therapy , interferon alfa , vasculitis , pathology , immunology , chemotherapy , disease , cancer research
We report two patients who developed intense livedo reticularis clearly related to the administration of interferon α 2b as an adjuvant therapy for melanoma. Histological studies showed scattered perivascular infiltrates without vasculitis. Laboratory tests excluded any underlying condition. Resolution of the symptoms was observed in both patients when interferon α was withdrawn. These cases highlight the occurrence of livedo reticularis as an uncommon side‐effect of interferon α treatment.