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PM‐SCL autoantibody positive scleroderma with polymyositis (mechanic's hand: clinical aid in the diagnosis)
Author(s) -
Török L,
Dankó K,
Cserni G,
Szûcs G
Publication year - 2004
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2004.00868.x
Subject(s) - medicine , autoantibody , polymyositis , dermatomyositis , interstitial lung disease , scleroderma (fungus) , pulmonary fibrosis , pathology , concomitant , dermatology , systemic scleroderma , fibrosis , lung , immunology , antibody , inoculation
This report concerns a 56‐year‐old‐woman presenting PM‐SCL autoantibody positive scleroderma with dermatomyositis (scleromyositis) and concomitant interstitial lung fibrosis. The recently observed overlapping syndrome is characterized by the presence of specific autoantibodies, HLA–type association and benign course. A new skin symptom (‘mechanic's hands’) predicts the disease, in particular the interstitial lung pathology, which is its most relevant internal manifestation.