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High‐performance liquid chromatographic determination of triclosan and triclocarban in cosmetic products
Author(s) -
Liu T.,
Wu D.
Publication year - 2012
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1468-2494.2012.00742.x
Subject(s) - triclosan , triclocarban , chromatography , chemistry , methanol , cosmetics , high performance liquid chromatography , organic chemistry , medicine , pathology
Synopsis A high–performance liquid chromatographic ( HPLC ) method for the determination of triclosan and triclocarban in cosmetic products was developed. Triclosan and triclocarban quantities in 168 of cosmetics were investigated and statistical analyzed with this method. The optimal condition are as follows: An A gilent SB ‐ C 8 analytical column (250 × 4.6 mm, 5μm) was utilized, and mixed buffer solution of methanol and 0.01 mol L −1 phosphate (p H 3.0) (72 : 28, V / V ) were used for isocratic elution at a total flow rate of 1.0 mL min −1 . It is found the calibration curves had a good linear regression with UV detection (280 nm) within test range of 0–110 μg mL −1 with the correlation coefficients of 0.999 in all cases. This method is simple, selective, convenient, and reproducible for the determination of triclosan and triclocarban in commercial cosmetic products.