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Metabolic Consequences of Forced Diuresis Following Prostatectomy
Author(s) -
MALONE P. R.,
DAVIES J. H.,
STANDFIELD N. J.,
BUSH R. A.,
GOSLING J. V.,
SHEARER R. J.
Publication year - 1986
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1986.tb09094.x
Subject(s) - diuresis , medicine , urology , prostatectomy , prospective cohort study , surgery , renal function , prostate , cancer
Summary— The efficacy and metabolic consequences of a standardised forced diuresis regime following prostatectomy were studied in three parts.1 A retrospective review of 372 patients. 2 A detailed prospective study of blood and urine electrolyte changes in 25 patients. 3 A prospective study of urinary oxalate levels in 15 patients.The regime was effective in safely preventing post‐operative clot retention. In 54% of patients the plasma sodium fell below 135 mmol/l. Hypokalaemia was mild and transient except in patients on long‐term diuretics. There was a significant per‐operative fall in serum calcium levels. It was concluded that forced diuresis is a safe and effective method of reducing clot retention following prostatectomy. The high incidence of post‐operative hyponatraemia suggests that absorption of glycine solution at transurethral prostatectomy is a common occurrence.