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A Comparison of Cephazolin Sodium and Co‐trimoxazole as Prophylactic Antibiotics in Out‐Patient Urinary Tract Endoscopy
Author(s) -
HART A. J. L.,
HOUSTON D. R.,
McALLISTER T. A.
Publication year - 1982
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1982.tb08957.x
Subject(s) - incidence (geometry) , medicine , urine , urinary system , endoscopy , antibiotics , intramuscular injection , anesthesia , microbiology and biotechnology , physics , optics , biology
Summary— Five hundred patients were entered into a study to compare intramuscular cephazolin sodium with intramuscular co‐trimoxazole in reducing the incidence of post‐endoscopy rigor in out‐patients. Urine cultures were carried out immediately before, immediately after, and 24 h after endoscopy and the incidence of post‐procedure symptoms was elicited by pre‐paid reply post cards. Similar rigor rates (9%) were obtained in the 2 groups. The incidence of sensitivity of the significant cultured organisms to the 2 antibiotics was high, but no correlation was found between the presence of infected urine and rigor, and possible reasons for this are discussed. Patients found intramuscular administration of co‐trimoxazole to be painful and the 10% incidence of rigor is no improvement on the 8% rigor rate obtained in those who received cephazolin.