Premium
THE COMPOSITION OF CALCULI FROM PATIENTS WITH ALCAPTONURIA
Author(s) -
Sutor D. June,
Wooley Susan E.,
Křížek V.
Publication year - 1970
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1111/j.1464-410x.1970.tb04470.x
Subject(s) - homogentisic acid , composition (language) , chemistry , calculus (dental) , mineralogy , medicine , art , dentistry , biochemistry , literature
SUMMARY The composition of the crystalline material present in 5 renal calculi and pieces of prostatic calculi from patients suffering from alcaptonuria has been determined by the X‐ray powder method. The urinary stones contain standard calculus constituents. Some of the pieces of the prostatic calculi consist of a substituted calcite Ca(Mg, Mn)CO 3 , a substance not reported hitherto in a calculus. The stones, which are very dark in colour, also contain a small amount of the crystalline melanin‐type oxidation product of homogentisic acid and probably a larger amount of the pigment in a finely divided or amorphous state.