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Solitary metastasis of a clear cell ovarian adenocarcinoma to the small bowel mucosa
Author(s) -
Nakamura Miwa,
Mitsuhashi Akira,
Tanaka Naotake,
Nagai Yuichiro,
Shozu Makio
Publication year - 2011
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2010.01355.x
Subject(s) - medicine , metastasis , cytokeratin , ovary , clear cell adenocarcinoma , ovarian carcinoma , pathology , clear cell carcinoma , adenocarcinoma , bowel resection , occult , ovarian tumor , carcinoma , ovarian cancer , clear cell , cancer , immunohistochemistry , alternative medicine
Abstract Metastasis of ovarian carcinoma to the small bowel parenchyma without peritoneal dissemination is uncommon. A 63‐year‐old woman underwent surgery for a clear cell adenocarcinoma of the ovary and received adjuvant chemotherapy. Eighteen months after the operation, she presented with recurrent occult bowel hemorrhage without evidence of an abdominal mass. Nine months later, a rapidly growing abdominal mass was detected. Laparoscopy revealed a solitary tumor of the ileum covered with an intact serosal layer. Partial ileectomy was performed for tumor resection. Histological examination revealed cells resembling the primary ovarian tumor in the mucosal surface of the small bowel along with an intact serosa. The tumor cells were positive for cytokeratin 7 and negative for cytokeratin 20, suggesting an ovarian origin. This is the first report of solitary metastasis of an ovarian carcinoma to the small bowel parenchyma without peritoneal dissemination. Metastasis to the small bowel should be considered in ovarian carcinoma patients with occult gastrointestinal hemorrhage.