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In Vitro Release of a Tumor‐Antigen (TA‐4) by Human Cervical Squamous Cell Carcinoma
Author(s) -
Aramaki Shojiro,
Kato Hiroshi,
Morioka Hitoshi,
Toyoshima Hiroyuki,
Torigoe Tadashi
Publication year - 1981
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1981.tb00530.x
Subject(s) - radioimmunoassay , antiserum , in vitro , incubation , cervix , antigen , basal cell , epithelium , carcinoma , squamous carcinoma , pathology , cell , chemistry , biology , cancer research , medicine , immunology , cancer , biochemistry
The release of a human squamous cell carcinoma antigen (TA‐4) was studied by in vitro incubation of squamous cell carcinoma tissues and normal squamous epithelium of the uterine cervix. TA‐4 activity was determined by a radioimmunoassay method using a monospecific antiserum to TA‐4. TA‐4 activity was found in both malignant and non‐malignant tissues. However, the malignant tissue released significantly larger amounts of TA‐4 than the non‐malignant tissue during 72 hours incubation.