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Filarial Chyluria Associated Glomerulonephritis and Therapeutic Considerations in the Chyluric Patient
Author(s) -
Waugh D. A.,
Alexander J. H.,
Ibels L. S.
Publication year - 1980
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1980.tb04977.x
Subject(s) - chyluria , medicine , filariasis , glomerulonephritis , wuchereria bancrofti , lymphatic filariasis , lymphatic system , pathology , immunology , kidney , helminths
Summary: Two patients with chyluria who were successfully treated by surgical disconnection of the lymphatics from the renal pelvis are reported. One patient also had an associated glomerulonephritis, possibly secondary to filariasis. Although glomerulonephritis associated with filariasis has been reported previously the details of renal biopsies in man have included only light microscopic findings. In this patient immunoflourescent and electron microscopic studies showed mesangial deposits of immunoglobulins and complement which suggests that glomerulonephritis in patients with filariasis may be of an immune complex type.