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Double squamous cell carcinomas, verrucous type and poorly differentiated type, of the urinary bladder unassociated with bilharzial infection
Author(s) -
Olda Yasuhisa,
Yasuda Masanori,
Kajiwara Hiroshi,
Onda Hajime,
Kawamura Nobuo,
Osamura R. Yoshiyuki
Publication year - 1997
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1997.tb04558.x
Subject(s) - verrucous carcinoma , pathology , squamous metaplasia , urinary bladder , carcinoma , basal cell , medicine , biology , epithelium
A case of a 66‐year‐old Japanese woman with two synchronous urinary biadder tumors, namely verrucous carcinoma and poorly differentiated squmamous cell carcinoma, is described. Both tumors were accompanled by widespread squamous metaplasia in the background and unassociated with bilharzial infection. The poorly differentiated squamous cell carcinoma, having a satellite tumor in Its proximlty, was large and in an advanced stage. The verrucous carcinoma was small with minimal invasion to the muscuiaris propria. The boundary between both tumors was well defined, suggesting colliding growth appearance. Immunoexpression of cytokeratins of verrucous carcinoma was simllar to that of squamous metaplasia, and significant differences between verrucous carcinoma and poorly differentiated squamous cell carcinoma were demonstrated in thair immunoexpression of cytokeratins.