Open AccessMALIGNANT LYMPHOEPITHELIAL LESION OF THE SUBMANDIBULAR GLAND
Author(s) -
Tada Toyohiro,
Wakabayashi Takashi,
Kishimoto Hidemasa
Publication year - 1983
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1983.tb02151.x
Subject(s) - submandibular gland , pathology , anaplasia , lesion , lymphatic system , medicine
A case of maligant lymphoepithelial lesion affecting the submandibular gland of a 48‐year‐old Japanese man is described. Histologically, a well‐encapsulated tumorous mass replacing almost the whole gland was composed of lymphoid and epithelial elements, and the latter revealed severe anaplasia with frequent mitotic figures indicating malignant changes. There is no sign of recurrence up to now, 32 months after the operation. Ultrastructural studies on a formalin‐fixed sampling from the gland demonstrated the squamous nature of the epithelial component. This is the first case of malignant lymphoepithelial lesion of the submandibular gland detected in Japan.