Open AccessTHE FIBRINOLYTIC ACTIVITY OF ISOLATED RAT GLOMERULI BY FIBRIN SLIDE TECHNIQUE
Author(s) -
Hara Masanori,
Kihara Itaru,
Morita Takashi,
Otte Takashi,
Yamamoto Tadashi
Publication year - 1981
Publication title -
acta patholigica japonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
ISSN - 0001-6632
DOI - 10.1111/j.1440-1827.1981.tb01369.x
Subject(s) - fibrin , fibrinolysis , pathology , nephritis , chemistry , medicine , immunology
A method for measurement of rat glomerular fibrinolysis and the results of its application to rat Masugi nephritis are described. The glomerular fibrinolytic activity was measured on isolated glomeruli using a fibrin slide technique. The procedure of this method is simple and the results obtained have a good reproducibility. By applying this method to rat Masugi nephritis, sequential changes in glomerular fibrinolytic activity could be assessed. A decrease in glomerular fibrinoloytic activity that was related to the extent of fibrin deposits in the glomeruli was demonstrated in the autologous phase.