Intraneuronal Polyglucosan Bodies and Peculiar Inclusions in the Midbrain‐Tegmentum of the Aged | Zendy

Ikeda Kenji | Zendy; Kosaka Kenji | Zendy; Hori Akira | Zendy

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Intraneuronal Polyglucosan Bodies and Peculiar Inclusions in the Midbrain‐Tegmentum of the Aged

Author(s) -

Ikeda Kenji,

Kosaka Kenji,

Hori Akira

Publication year - 1987

Publication title -

psychiatry and clinical neurosciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.609

H-Index - 74

eISSN - 1440-1819

pISSN - 1323-1316

DOI - 10.1111/j.1440-1819.1987.tb00430.x

Subject(s) - tegmentum , midbrain , anatomy , ultrastructure , pathology , medicine , biology , neuroscience , central nervous system

A small number of intraneuronal polyglucosan bodies, the so‐called Lafora bodies, is occasionally found in the tegmental areas of the midbrain in aged cases with no metabolic or degenerative diseases. The occasional appearance of peculiar bodies, which Kato et al. 1982 reported in a case of presenile dementia, is also observed during the examination of the inclusions. The ultrastructure of the bodies reveals an amorphous, electron‐dense central core and a peripheral zone of radially oriented 100 A wide filaments.

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