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Clear cell ependymoma: a mimicker of oligodendroglioma – report of three cases
Author(s) -
Jain Deepali,
Sharma Mehar Chand,
Arora Reena,
Sarkar Chitra,
Suri Vaishali
Publication year - 2008
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/j.1440-1789.2008.00895.x
Subject(s) - oligodendroglioma , ependymoma , medicine , pathology , ependymal cell , glioma , astrocytoma , immunohistochemistry , cancer research
Clear cell variant of ependymoma is a rare entity which morphologically mimics oligodendroglioma and poses a diagnostic dilemma. We describe three cases of clear cell ependymoma in male children which were supratentorial in location. On microscopic examination, these tumors were composed of sheets of clear cells and resembled oligodendroglioma. Electron microscopy confirmed the ependymal nature of these tumors. Clear cell ependymomas are rare and aggressive tumors. More cases need to be reported to determine their therapeutic responsiveness and prognosis.