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Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious puberty
Author(s) -
Johnson Stephanie R,
Nolan Richard C,
Grant Maree T,
Price Glynis J,
Siafarikas Aris,
Bint Lewis,
Choong Catherine SY
Publication year - 2012
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/j.1440-1754.2011.02083.x
Subject(s) - leuprorelin , medicine , central precocious puberty , depot , surgery , girl , precocious puberty , abscess , pediatrics , hormone , gonadotropin releasing hormone , luteinizing hormone , psychology , developmental psychology , archaeology , history
We describe a case of an 8 year old girl with central precocious puberty. She was commenced on 3 monthly intramuscular depot Leuprorelin acetate therapy, as a result of which she developed sterile abscesses. She was converted to daily subcutaneous Leuprorelin acetate therapy with no recurrence of the abscesses. The possible mechanisms for this reaction are described in the article.