Premium
Helicobacter pylori and hepatocellular carcinoma: Correlated or uncorrelated?
Author(s) -
Wu XiongZhi,
Chen Dan
Publication year - 2006
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1111/j.1440-1746.2006.04245.x
Subject(s) - hepatocellular carcinoma , medicine , helicobacter pylori , cirrhosis , gastroenterology , hepatitis c virus , carcinoma , risk factor , spirillaceae , virus , immunology , gastritis
Abstract Helicobacter pylori can be detected in liver tissue resected from patients with hepatocellular carcinoma. Conflicting reports regarding the relationship between H. pylori and hepatocellular carcinoma mean it is uncertain whether H. pylori acts as a troublemaker, co‐risk factor or innocent bystander to the development of hepatocellular carcinoma. Clinical studies in patients without known causes of hepatocellular carcinoma are important to discover whether H. pylori is involved in the carcinogenesis of hepatocellular carcinoma. High quality prospective studies in patients with hepatocellular carcinoma, hepatitis C virus infection and no cirrhosis are needed to determine whether H. pylori is a co‐risk factor for hepatocellular carcinoma.