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Multiple eruptive squamous cell carcinoma in a patient with chronic plaque psoriasis on adalimumab
Author(s) -
Simpkin Susan,
Oakley Amanda
Publication year - 2013
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2012.00920.x
Subject(s) - medicine , acitretin , psoriasis , adalimumab , dermatology , methotrexate , keratoacanthoma , isotretinoin , plaque psoriasis , basal cell , tumor necrosis factor alpha , pathology , acne
Abstract A 67‐year‐old man with chronic plaque psoriasis previously treated with psoralen plus PUVA, ciclosporin, methotrexate and acitretin developed eruptive squamous cell carcinoma after seven doses of adalimumab. We review the association of squamous cell carcinoma with immunosuppressive agents used for the treatment of chronic plaque psoriasis. Initiation of tumour necrosis factor (TNF)‐α inhibitors in a patient at high risk of non‐melanoma skin cancer may warrant chemoprophylaxis with acitretin.