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Methotrexate toxicity presenting as ulcerated psoriatic plaques
Author(s) -
Wong Suming,
Chong Yew Thong,
Thevarajah Suganthi,
Baba Roshidah
Publication year - 2012
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.2011.00779.x
Subject(s) - medicine , methotrexate , toxicity , dermatology , psoriasis , pathology
Methotrexate toxicity is known to cause erosions of existing psoriatic plaques, although rare. We describe two patients who developed painful ulcerated psoriatic plaques as an early presenting sign of methotrexate toxicity and review the risk factors associated with this manifestation.